Specialization profile--Biomedical technology and electronics

This profile concentrates on the design and development of circuits and (micro-)systems for biomedical applications.

Suggested courses

BM41055Anatomy and physiology4 EC details
EE4555Active implantable biomedical microsystems5 EC details
ET4127Themes in biomedical electronics4 EC details
ET4130Bioelectricity3 EC details
ET4252Analog integrated circuit design4 EC details
ET4257Sensors and actuators4 EC details
ET4260Microsystem integration4 EC details
ET4277Microelectronics reliability4 EC details
ET4391Advanced microelectronics packaging3 EC details
SC42025Filtering and identification6 EC details

MSc project proposals

Some examples of thesis topics (this list is not exhaustive):
BE[2024] 3D Printed Bioelectronics for Regenerative Medicine
[2024] Wireless Stimulation of the Brain with Light
[2024] Transparent Microelectrode Arrays for Neuron Recordings and Stimulation
[2024] Organic Electrochemical Transistors for Wound Healing
[2024] Conformable Microelectrode Arrays for Electrical Mapping of the Heart
[2023] Current driver circuit for power-efficient neural stimulation
[2023] Patch clamp experiments on activation behavior of cortical neurons to electrical stimulation
[2024] Ultrasound-guided Ultrasound Neuromodulation
[2021] Body Coupled Communication for Microscale Implants
[2020] Body-coupled communication to enhance IMD security
[2022] External electronics for ultrasonically powered stimulators
[2024] Smart transparent electrode array for electroceuticals
[2022] Ultra-Flexible Active-Matrix Electrophysiology Arrays for Neural Interfacing
[2024] Active neural interfaces for Bioelectronic Medicine (MSc project at Fraunhofer)
Ex-Situ Heart Perfusion (ESHP) sensor
ECTMOptimising RF spectroscopy for multi-layer spectrum extraction in organ-on-chip applications
Multi-sensor integration for broadband dielectric spectroscopy of Organ-on-Chip devices
Control electronics for soft actuator to stimulate cardiac cells in-vitro
Wafer-level fabrication of transparent 3D microelectrode arrays
EIMagneto-mechanical micro-antenna for implantable devices
Conformable CMOS-based implantable array for Brain-Computer Interfaces
Electro-optical device for ultra-low power communication
[2023] A Programmable High-Voltage Pulser for Miniature Ultrasound Probes
[2023] A Compact Noise-Shaping SAR ADC for Smart Ultrasound Probes
[2023] A compact ultrasound low-noise amplifier with built-in time-gain compensation
[2023] 3D Integration and Packaging Schemes for Smart Ultrasound Devices
[2023] Power management circuitry for battery-powered ultrasound patches
[2023] A transceiver ASIC for a wearable ultrasound patch
[2023] Data reduction by mixed-signal processing of ultrasound echo signals for wearable ultrasound devices
[2023] Shape Sensing for Flexible Ultrasound Transducer Arrays
A system for blood analysis of newborns using Microneedles

Thesis examples

BE 2024 Hsukang ChenArtifact-Free Neurostimulator with Arbitrary Waveform Generation for High-Channel, High-Density Bidirectional Neural Interfaces
2023 Yuan LeiAn Area- and Energy-Efficient Ultrasonic Pulser Based on Self-timed Stepwise Charging
Chunyan XueWearable Ultrasonic Vagus Nerve Stimulator
Yihao ZhangAn Energy-Efficient High-Voltage Pulser for 2D Ultrasound Phased-Array Transmitters
2021 Berend KoeleIntegrating Ultrasound Neuromodulation and Imaging. A System Concept for a Non-Invasive Image-Guided Vagus Nerve Stimulator
Aitor del Rivero CortázarMicroelectronic design of a pseudo voltage clamp for a 0.18um CMOS-based mesoscale neural interface for intracellular in-vitro recording and stimulation
Joey van RijnNear-Realtime Low Power Epileptic Seizure Detection Using ANNs
Ishaan GhoshCMOS driving channel for ultrasonic neurovascular stent
Xinyu YangUltrasound Transmitter for Non-invasive Vagus Nerve Stimulation
Emmanouil (Manos) KandilakisUltra-Low Energy Time-Mode ADC with Background Calibration for Biomedical Sensing Applications
2020 Francesc VarkevisserA Charge Controlled Switched-Voltage Mode Neurostimulator
Shuang WangAn ultrasound receiver channel for vagus nerve imaging
Asli YelkenciA 16-Channel CMOS Reconfigurable Recording Unit for Simultaneous In-Vitro Microelectrode Array and Current-Clamp Measurements
Caitlin RamseySafety Investigation of Millimeter Wave Radar to Monitor Vital Signs in the NICU
Shengjie ChenA 3-by-3 400-MHz LC microsensor array for wireless capacitive biosensing
Gayatri AgarwalPVT Tolerant Transconductor for Low-Voltage Highly-Selective High-Frequency Filter of MRI Front-end Receiver
Brian NanhekhanPWM-based Transthoracic Bioimpedance Analyzer for Detecting Heart Failures
Pedro Gaizka Zufiria GerbolesAn Efficacious and Safe Multichannel Neurostimulator Powered by an Ultrasonic Wireless Link
Tim HosmanHigh-density interconnect technology optimised for flexible implants
Alberto Gancedo ReguilonDesign and Analysis of a General Purpose Biosignal Acquisition System
2019 Anirudh Kumar ParagENMOS - Energy Module for Self-Sustainable Wearable Sensors
Aurojyoti DasMultichannel LC ADC to Record Atrial Electrograms
Yashwanth Sai Reddy VyzaCapacitive Microelectrode Arrays for In-Vitro Analysis of Neural Activity
Marc BisschopResistive Matching using an AC Boost Converter for Efficient Ultrasonic Wireless Power Transfer
Koen EmmerAnalysing the performance of KHFAC nerve block stimulation parameters
Gandhika WardhanaA Flexible Transparent Graphene Electrode Array for Spinal Cord Stimulation in Rats
2018 Gerard Baquer GómezOptimal stimulation waveform for efficacious high-frequency block of the pudendal nerve with minimized electrochemical damage: A computer simulation optimization approach
Dieuwert MulStochastic Resonance Analog-to-Digital Conversion -- 1-Bit Signal Acquisition Employing Noise
Tim SteunebrinkLow-power low-cost readout electronics for inductive vital-sign measurements
Minghui LiuPassive Wireless ECoG Monitoring On Multiple Subjects
2016 Yao LiA 0.6V Low Noise Current Generator for Bio-Impedance Measurements in 40nm CMOS
Qiuyang LinA 0.6V, 1 uW, Low-Power Low-Noise Instrumentation Amplifier for ECG/BioZ measurement in 40nm CMOS
Samprajani RoutStructured Electronic Design of High-Pass ∆Σ Converters and their application to cardiac signal acquisition
Joost KerpelsIn vivo multicell inferior olivary recordings: alternative design methods for creating cheap and flexible electrode structures
2015 Sander FondseSWEAT: Sleeping Wireless Energy Transfer And Trickle Charger
2014 Jialue WangDesign of a Boost DC-DC Converter for Energy Harvesting Applications in 40nm CMOS Process
Menno VastenholtA Sub-GHz UWB Correlation Receiver for Wireless Biomedical Communication
2013 Luis Carlos GutierrezAnalysis and Design of MHz-range Wireless Power Transfer Systems for Implantable Devices
2010 Mark StoopmanA Sub-GHz UWB Pulse Generator for Wireless Biomedical Communication
Cees-Jeroen BesA front-end for sensing the stimulation and response of auditory nerve cells
Senad HiseniUltra Low-Power Analog Integrated Circuits for Extracellular Action Potential Detection
2009 Marijn Van DongenA versatile output stage for implantable neural stimulators
S. Al-AhdabAn Ultra Low Power Fully Integrated Sensor Interface IC for Pacemakers
ECTM 2022 Bram den OudenDesign and characterization of an implantable system for shock free cardiac rhythm control
2021 Lovro IvančevićOoC-integrated impedance spectroscopy for blood-brain barrier integrity analysis
Shanliang DengAdvanced optoelectronics driver system for biomedical applications
2020 Joshua Teye3D Robotic Ultrasound System
Tim de RijkA 3D microelectrode array to record neural activity at different tissue depths
2019 Aoibhinn Larkin ReddingtonNoninvasive Hemodynamic Monitoring: Left Ventricular Pressure-Volume Loop Reconstruction
Roel StortelderLab-on-a-chip for individual cell response to light stimulation
2014 Berend van MeerDesign of Cytostretch Skin A human cell based stretchable, flexible and mass-producible skin tissue model for drug development
2011 Aashini GulatiA Micro Surgical Instrument for Age Related Macular Degeneration
Ting YanIntegrated water cooling for HIFU prostate ablation
2009 N.T. BokerPrototyping of a Stretchable Microelectrode Array for Cardiotoxicity Drug Screening
EI 2017 Yixin ShiA Low-Power Area-Efficient SAR-Assisted Hybrid ADC for Ultrasound Imaging
Weichen XuLow-Power Readout IC for a PMUT-based bladder scanner
2014 Ludovic RousselotAcoustical Monitoring of Model System for Vascular Access in Haemodialysis
Stephen Van 't HofIn-vitro waveguide system for the detection of Escherichia coli in drain fluid after colorectal anastomotic leakage
SPS 2017 Jelimo MaswanMultiway Component Analysis for the Removal of Far Ventricular Signal in Unipolar Epicardial Electrograms of Patients with Atrial Fibrillation
Xuefei YouFull-Custom Multi-Compartment Synaptic Circuits in Neuromorphic Structures
Peter StijnmanTransceive Phase Corrected Contrast Source Inversion-Electrical Properties Tomography

Contact person

For more information about the research group, possible thesis topics, and suggestions for your ISP:

prof.dr.ir. Wouter Serdijn

Bioelectronics Group

Department of Microelectronics