MSc thesis project proposal
Ultrasound neuromodulation on in-vitro neuronal cultures
Microelectrode arrays (MEA) enable the measurement and stimulation of the electrical activity of cultured cells, and they would benefit from the integration of other neuromodulation methods to study their effects on neurons. Focused ultrasound neuromodulation (FUS) can excite and inhibit the electrical activity of the nervous system in a non-invasive manner, and it can be focused with submillimetre precision, therefore allowing high stimulation selectivity.
The student will perform the assignment at ECTM:
- Duration: ~9 months.
- Location: Philips Research, High Tech Campus Eindhoven
- Collaboration with Erasmus MC for experiments on neurons
The expected activities to be carried out by the student are:
- Characterization of the ultrasound transducers
- Design and assembly of an experimental setup to integrate the ultrasound system with the MEA recording system
- Design of the experiment and data analysis
You are a motivated student eager for challenges. You have an electronics or biomedical background, and some programming skills. Knowledge on ultrasound and electrophysiology is very welcome but not a requirement. A pro-active attitude and good English communication skills are expected.
MSc Marta Saccher
Electronic Components, Technology and Materials Group
Department of Microelectronics
Last modified: 2023-01-12